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Compared to either subcomponent alone, the hydrogel/ADSC-EV complex enhances healing efficacy by promoting skin wound healing and re-epithelialization, stimulating collagen production, and elevating the expression of Ki67, -smooth muscle actin (-SMA), CD31, and skin barrier proteins while suppressing the expression of inflammatory factors [147]

These findings suggest that MET-097 not only induces significant short-term weight loss but also has the potential for durable efficacy with relatively few doses

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