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Some studies were conducted in Asia and others only in Europe, precluding the application of the results to populations of different ethnic backgrounds

En todos los casos se cumple la normativa sobre proteccin de animales utilizados para experimentacin establecida por la administracin (Real Decreto 223/1988)

Higher doses have been associated with stronger metabolic effects in research settings, although the ideal dose differs between individuals

This conversion process is mediated by an enzyme called argininosuccinate synthase (ASS), which combines L-citrulline with another amino acid called aspartate to produce L-arginine