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The meta-analysis reported an odds ratio of 28.04 for injection site reactions compared to placebo

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Thats because peptides can easily break down in the digestive tract and are often too molecularly large to permeate the intestinal wall.20 Oral alternatives may use technologies like protective capsules and permeability agents to bypass these obstacles, but injection remains the most common peptide delivery method.20 Collagen peptides are an exception

Proteins were then electro-transferred to an Immobilon PVDF membrane (Millipore, Burlington, MA) followed by blocking in 5% wt/vol blocking buffer (Bio-Rad Laboratories) for 1 h at room temperature