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Both types of PE-AA oxidation, enzymatic (by lipoxygenase) and non-enzymatic (by autooxidation to PE-AA-OOH), eventually result in cell death [18, 30,31,32]

10.3390/metabo1412067939728460 80 Cutler RG, Camandola S, Feldman NH, et al

10.1186/1550-2783-9-7 [DOI] [PMC free article] [PubMed] [Google Scholar] Xing D, Yoo C, Gonzalez D, Jenkins V, Nottingham K, Dickerson B et al (2021) Dose-response of Paraxanthine on cognitive function: a double blind, placebo controlled, crossover trial

Perinatal administration of a selective serotonin reuptake inhibitor induces impairments in reproductive function and follicular dynamics in female rat offspring