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Accessed on February 26, 2017

A hallmark of ferroptotic initiation and execution is the upregulated peroxidation of phospholipid-bound polyunsaturated fatty acids (PUFAs) within cellular membranes, a process facilitated by labile iron pools (LIPs) and amplified through autocatalytic radical reactions (13,14)

Medication management strategies: If respiratory symptoms are temporally related to GLP-1 therapy and no alternative explanation is identified, several approaches may be considered: Dose adjustment: Reducing the dose or slowing the titration schedule according to FDA-approved labeling may alleviate symptoms if they are related to medication effects or gastrointestinal complications

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