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1A) However, when assessing individual protein differences where a specific protein signal had to be present in at least 75% of the participants, we showed that 28 proteins were significantly increased, and 5 proteins significantly reduced in children affected with konzo versus unrelated/unaffected individuals (q 0.5) (Fig

Conclusions and discussion Here we report the discovery of a set of hit fragments that bind to the TIN2 TBM binding site of the TRFH homodimerisation domain of TRF1