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While the supplements packaging notes it does not contain synthetic GLP-1 and is not a substitute for GLP-1 agonist drugs, Konzier said she viewed it as a more natural route to support weight management than taking a prescription drug

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Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis

Although the mechanisms remain unknown, researchers present their theory claiming that the thickening rigidity coexists with SIBO because of overgrowth by certain bacterial strains already present (Felice et al., 2016)