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Moreover, the clinical significance of lean mass loss cannot be inferred solely from quantitative measures, as muscle quality, strength, and metabolic function may be preserved or even improved in some contexts [15,16,17]

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Despite their diverse etiologies, these diseases converge on several recurring pathological themes, including oxidative stress, chronic inflammation, hormonal imbalance, aberrant extracellular matrix deposition, and dysregulated cell survival

Firstly, this is the first meta-analysis to evaluate the relationship between GLP-1RAs and the risk of respiratory disease in greater detail