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In MDD, this peripheral-central coupling is likely amplified by BBB dysfunction characterized by increased permeability, neurovascular inflammation, and associations with symptom severity [172, 173] thereby lowering the threshold at which peripheral KP activation translates into central glutamatergic, oxidative, and neuroimmune dysregulation

With regular sessions, patients notice a gradual brightening effect, fading of dark spots, and an overall glow

Furthermore, the integration of nanotechnology with TCM enhances therapeutic outcomes by improving drug bioavailability and enabling precise targeting of lung pathology, thus offering innovative treatments that address oxidative stress and inflammation in PF