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The role of glutathione Even though involvement of genetic abnormalities in autism spectrum disorders (ASD) is well-accepted, recent studies point to an equal contribution by environmental factors, particularly environmental toxicants

The zebrafish model has emerged as a powerful system for deconstructing this complexity (Table 3), owing to its high evolutionary conservation in liver morphology and function, including a well-characterized suite of CYP450 enzymes and a drug metabolism system that parallels human pathways (Goldstone et al., 2010)

These reactions are typically transient and resolve within 24-48 hours