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Good electron flow = healthy, energetic, long life Poor electron flow = low energy shorter lifespan/healthspan No electron flow = death Anything that impedes the flow of electrons in the body or robs them from the cells and tissues has negative health consequences
IL36RN mutations affect protein expression and function: a basis for genotypephenotype correlation in pustular diseases
Collectively, these findings indicate that non-selective or excessive chelation of brain iron may disrupt physiological metallostasis, emphasizing the need for precisely titrated, brain-targeted anti-ferroptotic interventions with balanced efficacytoxicity profiles. Beyond traditional chelators, several natural compounds have also shown potential in regulating iron transport proteins
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