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CAV-1 reduction induces Janus kinase (JAK)/STAT pathway activation in psoriatic inflammation, leading to further keratinocyte proliferation and cytokine/chemokine production

GLP-1 medications are very expensive, but a weekly injection (or a pill) is much easier to bring to a broad population of those who are obese than major surgery requiring a multidisciplinary team

For one, Ozempic and Wegovy are both given by weekly injection while Rybelsus is a daily tablet you swallow

These findings suggest that PhA could be a useful non-invasive marker of inflammation to consider in the management of patients with PWS [80]