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Meanwhile, on Tuesday, Novo announced that its triple-G agonist, UBT251, led to 19.7% weight loss after 24 weeks in a Phase 2 trial based in China

Gallstones and Gallbladder Disease Rapid weight loss, especially more than 1% of body weight per week, can increase the risk of gallstone formation by changing how bile is made and released

Here is how to manage them

When to seek urgent care: Severe or persistent nausea and vomiting leading to dehydration contact NHS 111 or your trial team Sudden, severe abdominal pain seek urgent medical attention Signs of a severe allergic reaction (anaphylaxis), including rash, swelling of the face, lips, or throat, or difficulty breathing call 999 immediately Upper right abdominal pain, fever, or jaundice seek medical attention Any new or worsening symptoms following an injection contact your trial team Reporting side effects: Patients and healthcare professionals are encouraged to report suspected adverse reactions via the MHRA Yellow Card Scheme at yellowcard.mhra.gov.uk or via the Yellow Card app