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What research suggests about GLP-1 inhibitors, absorption, and safer contraception choices If you have endometriosis or adenomyosis and youre using (or considering) a GLP1 medication for weight loss, diabetes or off-label endo treatmentsuch as semaglutide, liraglutide, or tirzepatideits reasonable to worry about a very practical question: Could this make my oral contraceptives less effective