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F.2 Sensorgrams from Adaptyv and Sino Biological We provide all sensorgrams from Adaptyv Bio and Sino Biological for download here for miniprotein designs ( and nanobody designs ( F.3 Additional Tables and Figures Acknowledgments We would like to thank Rachel Wu, Sergey Ovchinnikov, Wenxian Shi, Tally Portnoi, Umesh Padia, Peter Mikhael, Edwin Neumann, Christopher Garcia, Kevin Jude, Juno Nam, Cora Wendlandt, Dane Wittrup, Bradley Pentelute, Jigar Patel, Reda Rawi, Sarah Fahlberg, Kellon Belfon, Giannis Daras, Sushil Mishra, Mathai Mammen, Noah Getz, Bowen Jing, Donovan Chin, Thomas Schwartz, Jeremie Alexander, Jonathan Stokes, Robert Hurt, Matthew Shoulders, Robbie Wilson, Aneesh Karatt-Vellatt, and Soojung Yang for insightful discussions and feedback

The findings should be interpreted with caution as there were some methodological flaws, as a number of studies were judged to be either at high or unclear risk of bias for many domains, the review states