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However, heat stress-induced upregulation of HSF1 and HSP70 silences macroautophagy stimulators such as mitogen-activated protein kinase (MAPK) through mechanisms involving the mammalian target of rapamycin (mTOR) pathway (Sattari et al., 2025)

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Seek urgent medical attention if you develop: Severe, persistent abdominal pain (with or without vomiting), which could indicate pancreatitis Right upper abdominal pain or yellowing of the skin/eyes, which might suggest gallbladder problems Signs of severe dehydration such as extreme thirst, confusion, dizziness, or very dark urine For severe symptoms, call 999 or go to A&E