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A study published in the Journal of Clinical, Cosmetic, and Investigational Dermatology found that oral glutathione supplementation improved skin elasticity and reduced wrinkles in participants after several weeks of consistent use

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Neurosci Biobehav Rev 21:15166, PMID: 9062938 Stewart VC, Stone R, Gegg ME, Sharpe MA, Hurst RD, Clark JB, Heales SJ (2002) Preservation of extracellular glutathione by an astrocyte derived factor with properties comparable to extracellular superoxide dismutase