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A group size of six animals per arm was selected, consistent with commonly used cohort sizes in early-stage in vivo efficacy studies, and was sufficient to enable comparative survival analysis and evaluation of treatment-associated trends
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4.1.3 Advantages associated with the condition of dry eye disease Recent research has uncovered dissimilarities between DED patients and controls by examining carnitine levels in the tears of DED patients, indicating a possible link between the onset of DED and insufficient carnitine in the tear film
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