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However, most degradation is invisible at the molecular level

The Gut-Brain Axis and the Vagus Nerve The GLP-1 produced in the intestines after a meal also plays a role in suppressing eating, likely through different circuits than those GLP-1-expressing neurons found in the brain stem

This pattern is similar to whats been seen with other medications in this class

Certain supplements may be helpful when taking a GLP-1 drug, but others should be used with caution or avoided, and it may be important to monitor levels of particular vitamins and minerals