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These conditions include tropical sprue, and nontropical sprue (idiopathic steatorrhea, gluten-induced enteropathy)

In CKD, uremic toxin accumulation (e.g., indoxyl sulfate, acrolein), impaired antioxidant defense systems, and persistent inflammation collectively promote excessive production of reactive oxygen species (ROS), which disrupt erythrocyte membrane integrity, activate Ca 2+ -permeable cation channels, and trigger downstream eryptotic events (e.g., phosphatidylserine (PS) externalization, cell shrinkage, and cytoskeleton degradation) (Bissinger et al., 2019)

The IC 50 concentrations of both compounds were dosed followed by successive dilutions, aiming to identify the doses at which the two drugs yield the IC 50 concentration

Was identity confirmed by mass spectrometry