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Semaglutide binds to GLP-1 receptors in multiple tissues throughout the body, including the pancreas, gastrointestinal tract, and specific regions of the brain involved in appetite regulation

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Acknowledgments This research was supported by the Experimental Cancer Medicine Centre at King's College London, Cancer Research UK (AJR) and also by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and King's College London