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10.4103/bc.bc_21_21 [DOI] [PMC free article] [PubMed] [Google Scholar] Chiou H.-Y., Lin M.-W., Hsiao P.-J., Chen C.-L., Chiao S., Lin T.-Y., et al

Using its own set of genes, the autophagy pathway communicates with virtually all signaling networks and organelles

Further compounding the problem is the absence of sufficient patient persistence on the drugs: A relatively large portion of patients discontinue these medications within one year , with numbers increasing by the end of years two and three