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In phase II detoxification, glutathione conjugates electrophilic xenobiotics such as reactive drug metabolites, pesticide breakdown products, and lipid peroxidation aldehydes, rendering them more water-soluble for biliary or urinary excretion

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Recent patents on CNS drug discovery 3(2):112127 ONeill BT, Lauritzen HP, Hirshman MF, Smyth G, Goodyear LJ, Kahn CR (2015) Differential role of insulin/IGF-1 receptor signaling in muscle growth and glucose homeostasis