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The average (mean SD) METH consumption during the second week of operant training was 1.00 0.38 mg/kg in the ShA study and 5.23 2.30 mg/kg in the ExA study

Rapamycin, an inhibitor of mammalian target of rapamycin (mTOR) complex 1, exhibits cardioprotective effects in ferroptotic cells, where mTOR overexpression protects against iron-overload-induced cell death, a process exacerbated by mTOR deficiency (67, 68)