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Gastrointestinal issues Diabetic retinopathy Acute gallbladder disease Cholelithiasis, cholecystitis, biliary colic, cholecystectomy, Jaundice or clay coloured stools are common possible complications

However, neither study was sufficiently powered to produce meaningful conclusions about GLP-1 receptor agonists in HFrEF 132,133

G6PD Screening: Some doctors check for a specific enzyme deficiency before high-dose antioxidant therapy

These products typically claim to support or stimulate GLP1, but are not supported by randomized controlled trials demonstrating increased GLP1 levels or weight loss or glycemic benefits in humans